Dr. Rath defined a new direction in cancer research by shifting its primary focus from eliminating cancer cells to addressing a common pathomechanism of all cancers, which is the degradation of the surrounding connective tissue. This mechanism is a precondition for cancer metastasis (the main cause of death from cancer), tumor growth, angiogenesis and other aspects of malignancy. He suggested that the amino acid lysine and vitamin C could effectively control this process as the necessary components for optimum strength and stability of collagen and connective tissue in the body.
Cancer develops when cells in one part of an organ in the body escape growth control. Normal body cells grow, divide, and die in a systematic way. During childhood normal cells divide more frequently until the person becomes an adult. Upon reaching adulthood, the cells in most organs of the body divide only to replace dysfunctional or dying cells and to repair injuries. In the case of cancer cells, the genetic program that regulates the cell growth cycle becomes interrupted, causing the cells to become immortal and to constantly divide. Cancer cell growth never stops. Growing cells expand in a tissue by digesting the surrounding collagen and connective tissue barrier with specific enzymes; the most prominent are matrix metalloproteinases or MMPs. This cell growth results in the formation of a tumor mass.
The same process of collagen digestion is used by cancer cells to spread to other organs (metastasis). To stop cancer metastasis, the activity of MMPs must be inhibited. Dr. Rath and his team of researchers at the Dr. Rath Research Institute have identified a specific combination of nutrients that can inhibit the activity of MMPs and stop the spread of cancer cells. This nutrient combination includes vitamin C, the amino acids L-lysine and L-proline, a green tea extract known as Epigallocatechin Gallate (EGCG), and other micronutrients which work synergistically. Our extensive research conducted on more than two dozen cancer cell types have shown that this nutrient combination is effective in controlling cancer in multiple ways: stopping its growth, spread, formation of new blood vessels in tumors (angiogenesis) and inducing natural cancer cell death (apoptosis).
For scientific foundation of this approach, please read Dr. Rath’s publication